PKC zeta 抗体 (AA 408-412)
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Quick Overview for PKC zeta 抗体 (AA 408-412) (ABIN5689326)
抗原
See all PKC zeta (PRKCZ) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 408-412
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特异性
- This antibody detects endogenous levels of total PKCzeta protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- PKCzeta (Ab-410) antibody was raised against a peptide sequence around aa. 408~412 ( T-S-T-F-C) derived from PKCzeta .
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应用备注
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
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别名
- PKCzeta
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背景
- This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
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分子量
- 78 kDa
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基因ID
- 5590
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NCBI登录号
- NP_002735
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UniProt
- Q05513
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途径
- NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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