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NF-kB p65 抗体

Cited in 1 publication. The 小鼠 单克隆 anti-NF-kB p65 antibody (Clone 12G3) (ABIN5675549) specifically detects NF-kB p65 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN5675549
发货至: 中国
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Quick Overview for NF-kB p65 抗体 (ABIN5675549)

抗原

See all NF-kB p65 (NFkBP65) 抗体
NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This NF-kB p65 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

12G3
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human NFKB p65

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Pelgrim, Peterson, Gosker, Schols, van Helvoort, Garssen, Folkerts, Kraneveld: "Psychological co-morbidities in COPD: Targeting systemic inflammation, a benefit for both?" in: European journal of pharmacology, Vol. 842, pp. 99-110, (2019) (PubMed).

  • 抗原

    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

    别名

    NFKB p65

    背景

    Synonyms: NF kB P65, NF-kB p65, NFKBp65, NF-_Bp65, NF-kBp65, Avian reticuloendotheliosis viral (v rel) oncogene homolog A, MGC131774, NFKB 3, NFKB3, Nuclear Factor NF Kappa B p65 Subunit, Nuclear factor of kappa light polypeptide gene enhancer in B cells 3, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells, p65, p65 NF kappaB, p65 NFkB, RELA, Transcription Factor p65, v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)), V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A, v rel reticuloendotheliosis viral oncogene homolog A (avian), v-rel reticuloendotheliosis viral oncogene homolog A, p65NFKB, TF65_HUMAN.NF_B-p65, NF_B p65, NF _B-p65, NF_Bp65,

    Background: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

    基因ID

    5970

    UniProt

    Q04206

    途径

    NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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