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TARDBP 抗体 (AA 1-260)

This anti-TARDBP antibody is a 小鼠 多克隆 antibody detecting TARDBP in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN565079
发货至: 中国

Quick Overview for TARDBP 抗体 (AA 1-260) (ABIN565079)

抗原

See all TARDBP 抗体
TARDBP (TAR DNA Binding Protein (TARDBP))

适用

  • 90
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  • 12
  • 8
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  • 7
  • 6
  • 6
  • 5
  • 4
  • 4
  • 3
  • 1

宿主

  • 91
  • 21
  • 1
小鼠

克隆类型

  • 76
  • 37
多克隆

标记

  • 75
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TARDBP antibody is un-conjugated

应用范围

  • 92
  • 51
  • 38
  • 35
  • 27
  • 19
  • 15
  • 15
  • 13
  • 13
  • 4
  • 4
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  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 9
    • 8
    • 7
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    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-260

    原理

    Mouse polyclonal antibody raised against a partial recombinant TARDBP.

    序列

    MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    TARDBP (NP_031401.1, 1 a.a. ~ 260 a.a) partial recombinant protein with GST tag.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    50 % glycerol

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Ayala, Granado-Serrano, Cacabelos, Naudí, Ilieva, Boada, Caraballo-Miralles, Lladó, Ferrer, Pamplona, Portero-Otin: "Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS." in: Acta neuropathologica, Vol. 122, Issue 3, pp. 259-70, (2011) (PubMed).

    Tatom, Wang, Dayton, Skalli, Hutton, Dickson, Klein: "Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 17, Issue 4, pp. 607-13, (2009) (PubMed).

    Schwab, Arai, Hasegawa, Akiyama, Yu, McGeer: "TDP-43 pathology in familial British dementia." in: Acta neuropathologica, Vol. 118, Issue 2, pp. 303-11, (2009) (PubMed).

    Johnson, McCaffery, Lindquist, Gitler: "A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 17, pp. 6439-44, (2008) (PubMed).

    Schwab, Arai, Hasegawa, Yu, McGeer: "Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease." in: Journal of neuropathology and experimental neurology, Vol. 67, Issue 12, pp. 1159-65, (2008) (PubMed).

  • 抗原

    TARDBP (TAR DNA Binding Protein (TARDBP))

    别名

    TARDBP

    背景

    Full Gene Name: TAR DNA binding protein
    Synonyms: ALS10,TDP-43

    基因ID

    23435

    NCBI登录号

    NM_007375

    途径

    Positive Regulation of Peptide Hormone Secretion
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