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L1CAM 抗体

L1CAM 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647757
发货至: 中国
  • 抗原 See all L1CAM 抗体
    L1CAM (L1 Cell Adhesion Molecule (L1CAM))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 78
    • 24
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    克隆类型
    • 68
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    多克隆
    标记
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    This L1CAM antibody is un-conjugated
    应用范围
    • 52
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids NMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPW were used as the immunogen for the L1CAM antibody.
    亚型
    IgG
    Top Product
    Discover our top product L1CAM Primary Antibody
  • 应用备注
    Optimal dilution of the L1CAM antibody should be determined by the researcher.\. IHC (FFPE): 1-2 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the L1CAM antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    L1CAM (L1 Cell Adhesion Molecule (L1CAM))
    别名
    L1CAM / NCAM-L1 / CD171 (L1CAM 产品)
    别名
    l1cam-a antibody, CAML1 antibody, CD171 antibody, HSAS antibody, HSAS1 antibody, MASA antibody, MIC5 antibody, N-CAM-L1 antibody, N-CAML1 antibody, NCAM-L1 antibody, S10 antibody, SPG1 antibody, L1 antibody, Hsas antibody, Hyd antibody, NCAML1 antibody, L1 cell adhesion molecule S homeolog antibody, L1 cell adhesion molecule antibody, l1cam.S antibody, L1CAM antibody, L1cam antibody
    背景
    L1, also known as L1CAM, is a transmembrane protein member of the L1 protein family, encoded by the L1CAM gene. The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
    UniProt
    P32004
    途径
    Synaptic Membrane
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