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YAP1 抗体 (AA 53-161)

Name: YAP1 抗体 (AA 53-161)
SKU: ABIN564526
Availability: OutOfStock

Cited in 17+ publications. This anti-YAP1 antibody is a 小鼠单克隆 antibody detecting YAP1 in WB, ELISA, IF 和 IHC (p). Suitable for 人.

Western Blot analysis of YAP1 expression in transfected 293T cell line by YAP1 monoclonal antibody (M01), clone 2F12. (YAP1 抗体 (AA 53-161))

Immunofluorescence of monoclonal antibody to YAP1 on HeLa cell. (YAP1 抗体 (AA 53-161))

Detection limit for recombinant GST tagged YAP1 is approximately 0. (YAP1 抗体 (AA 53-161))

ELISA

Immunoprecipitation of YAP1 transfected lysate using anti-YAP1 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with YAP1 MaxPab rabbit polyclonal antibody. (YAP1 抗体 (AA 53-161))

Western Blot detection against Immunogen (37. (YAP1 抗体 (AA 53-161))

Immunoperoxidase of monoclonal antibody to YAP1 on formalin-fixed paraffin-embedded human endometrium. (YAP1 抗体 (AA 53-161))

ISt

YAP1 monoclonal antibody (M01), clone 2F12. (YAP1 抗体 (AA 53-161))

7 images

(17 references)

产品编号 ABIN564526

发货至: 中国

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中国
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Quick Overview for YAP1 抗体 (AA 53-161) (ABIN564526)

抗原

See all YAP1 抗体

YAP1 (Yes-Associated Protein 1 (YAP1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This YAP1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2F12

抗原表位
45

15

15

6

6

5

5

4

4

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 53-161

原理

Mouse monoclonal antibody raised against a partial recombinant YAP1.

序列

QIVHVRGDSE TDLEALFNAV MNPKTANVPQ TVPMRLRKLP DSFFKPPEPK SHSRQASTDA GTAGALTPQH VRAHSSPASL QLGAVSPGTL TPTGVVSGPA ATPTAQHLR

交叉反应

人, 小鼠

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

YAP1 (NP_006097, 53 a.a. ~ 161 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG2a
anti-Yes-Associated Protein 1 (YAP1) antibody
YAP1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) antibody
YAP1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1A12 unconjugated

anti-Yes-Associated Protein 1 (YAP1) (AA 131-330) antibody
YAP1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) (C-Term) antibody
YAP1 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 绵羊, Cow, 马, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) (AA 53-162) antibody
YAP1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated

anti-Yes-Associated Protein 1 (YAP1) antibody
YAP1 适用: 人 WB, FACS, IHC (p), EIA 宿主: 小鼠 Monoclonal 1A12 unconjugated

anti-Yes-Associated Protein 1 (YAP1) (pSer127) antibody
YAP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) (Internal Region) antibody
YAP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) (pSer127) antibody
YAP1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Yes-Associated Protein 1 (YAP1) antibody
KO Validated YAP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3225 unconjugated Recombinant Antibody

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Toyooka, Oka, Fujimori: "Early preimplantation cells expressing Cdx2 exhibit plasticity of specification to TE and ICM lineages through positional changes." in: Developmental biology, Vol. 411, Issue 1, pp. 50-60, (2016) (PubMed).

Abbassi, Malki, Cockburn, Macaulay, Robert, Rossant, Clarke: "Multiple Mechanisms Cooperate to Constitutively Exclude the Transcriptional Co-Activator YAP from the Nucleus During Murine Oogenesis." in: Biology of reproduction, Vol. 94, Issue 5, pp. 102, (2016) (PubMed).

Junemann, Birgin, Erdmann, Schröder, Just, Gerhard, Pich: "Toxin A of the nosocomial pathogen Clostridium difficile induces primary effects in the proteome of HEp-2 cells." in: Proteomics. Clinical applications, Vol. 11, Issue 3-4, (2016) (PubMed).

Yang, Zhang, Chen, Chen, Dong: "Oncoprotein YAP regulates the spindle checkpoint activation in a mitotic phosphorylation-dependent manner through up-regulation of BubR1." in: The Journal of biological chemistry, Vol. 290, Issue 10, pp. 6191-202, (2015) (PubMed).

Shao, Zhai, Del Re, Sciarretta, Yabuta, Nojima, Lim, Pan, Sadoshima: "A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response." in: Nature communications, Vol. 5, pp. 3315, (2014) (PubMed).

Adler, Heller, Bringman, Ranahan, Cocklin, Goebl, Oh, Lim, Ingham, Wells: "Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth." in: The Journal of biological chemistry, Vol. 288, Issue 21, pp. 15181-93, (2013) (PubMed).

Das, Tanigawa, Karner, Xin, Lum, Chen, Olson, Perantoni, Carroll: "Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation." in: Nature cell biology, Vol. 15, Issue 9, pp. 1035-44, (2013) (PubMed).

Yang, Zhang, Liu, Chong, Ding, Chen, Dong: "CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation." in: Cancer research, Vol. 73, Issue 22, pp. 6722-33, (2013) (PubMed).

Adler, Johnson, Heller, Bringman, Ranahan, Conwell, Sun, Hudmon, Wells: "Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 43, pp. 17368-73, (2013) (PubMed).

Skouloudaki, Walz: "YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35735, (2012) (PubMed).

Hirate, Cockburn, Rossant, Sasaki: "Tead4 is constitutively nuclear, while nuclear vs. cytoplasmic Yap distribution is regulated in preimplantation mouse embryos." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 50, pp. E3389-90; author reply E3391-2, (2012) (PubMed).

Murakami, Mizuno, Taniguchi, Fujii, Ishiguro, Fukui, Akatsuka, Horio, Hida, Kondo, Toyokuni, Osada, Sekido: "LATS2 is a tumor suppressor gene of malignant mesothelioma." in: Cancer research, Vol. 71, Issue 3, pp. 873-83, (2011) (PubMed).

Leivonen, Rokka, Ostling, Kohonen, Corthals, Kallioniemi, Perälä: "Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 7, pp. M110.005322, (2011) (PubMed).

Sekido: "Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation." in: Pathology international, Vol. 61, Issue 6, pp. 331-44, (2011) (PubMed).

Wada, Itoga, Okano, Yonemura, Sasaki: "Hippo pathway regulation by cell morphology and stress fibers." in: Development (Cambridge, England), Vol. 138, Issue 18, pp. 3907-14, (2011) (PubMed).

Tomlinson, Gudmundsdottir, Luong, Leung, Knebel, Basu: "JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis." in: Cell death & disease, Vol. 1, pp. e29, (2011) (PubMed).

Lau, Murray, Houshmandi, Xu, Gutmann, Yu: "Merlin is a potent inhibitor of glioma growth." in: Cancer research, Vol. 68, Issue 14, pp. 5733-42, (2008) (PubMed).
抗原

YAP1 (Yes-Associated Protein 1 (YAP1))

别名

YAP1

背景

Full Gene Name: Yes-associated protein 1, 65 kDa
Synonyms: YAP,YAP2,YAP65,YKI

基因ID

10413

NCBI登录号

NM_006106

途径

MAPK Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha