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PCNA 抗体
PCNA
适用: 人, 小鼠, 大鼠, 小鸡, Drosophila melanogaster, Non-Human Primate
WB, FACS, IHC (p), IP, ICC, IHC (fro)
宿主: 小鼠
Monoclonal
PC10
unconjugated
PCNA抗体详情
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抗原
See all PCNA 抗体
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
适用
All reactivities for PCNA 抗体
人, 小鼠, 大鼠, 小鸡, Drosophila melanogaster, Non-Human Primate
宿主
All hosts for PCNA 抗体
小鼠
克隆类型
All clonalities for PCNA 抗体
单克隆
标记
All conjugates for PCNA 抗体
This PCNA antibody is un-conjugated
应用范围
All applications for PCNA 抗体
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
特异性
The mouse monoclonal antibody PC10 (also known as 3F81) recognizes PCNA, a 36 kDa conserved nuclear protein serving as a cofactor for DNA synthesis.
交叉反应 (详细)
Human, Non-Human Primates, Mouse, Rat, Chicken, Drosophila
纯化方法
Purified by protein-A affinity chromatography.
纯度
> 95 % (by SDS-PAGE)
免疫原
recombinant rat PCNA
克隆位点
PC10
亚型
IgG2a kappa
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Discover our top product PCNA Primary Antibody
Alternatives
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使用细节
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应用备注
Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
限制
仅限研究用
贮存及处理
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浓度
1 mg/mL
缓冲液
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
Store at 2-8°C. Do not freeze.
PCNA目标详情
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抗原
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
别名
PCNA (PCNA 产品 )
别名
PCNAR antibody, Pcna/cyclin antibody, pcna antibody, AO090003000846 antibody, 53/13 antibody, CG9193 antibody, DmPCNA antibody, Dmel\\CG9193 antibody, MUS209 antibody, Mus209 antibody, PCNA antibody, PCNA/mus209 antibody, Pcna antibody, dPCNA antibody, l(2)02448 antibody, l(2)56F antibody, l(2)56Fa antibody, l(2)s1534 antibody, cb16 antibody, fb36g03 antibody, wu:fa28e03 antibody, wu:fb36g03 antibody, pcna-A antibody, proliferating cell nuclear antigen antibody, DNA polymerase III sliding clamp antibody, Proliferating cell nuclear antigen antibody, Proliferating cell nuclear antigen-like antibody, proliferating cell nuclear antigen L homeolog antibody, proliferating cell nuclear antigen 1 antibody, PCNA antibody, Pcna antibody, pcna antibody, MMP_RS08810 antibody, ANI_1_512014 antibody, AOR_1_1500154 antibody, MGC53867 antibody, pcna.L antibody, pcna1 antibody, LOC106420145 antibody, pcn1 antibody
背景
Proliferating cell nuclear antigen,PCNA (proliferating cell nuclear antigen) is the DNA polymerase delta auxiliary protein acting in homotrimeric form to increase the processivity of leading strand synthesis during DNA replication. PCNA is expressed in the nucleus of all proliferating cells. In response to DNA damage, it is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. PCNA is a useful marker of DNA synthesis, as its form not involved in DNA synthesis degradates in histological preparations in the presence of organic solvents.,ATLD2
基因ID
5111
UniProt
P12004
途径
Telomere Maintenance , DNA Damage Repair , Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA , Autophagy
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