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PCNA 抗体

PCNA 适用: 人, 小鼠, 大鼠, 小鸡, Drosophila melanogaster, Non-Human Primate WB, FACS, IHC (p), IP, ICC, IHC (fro) 宿主: 小鼠 Monoclonal PC10 unconjugated
产品编号 ABIN5633264
发货至: 中国
  • 抗原 See all PCNA 抗体
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    适用
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    人, 小鼠, 大鼠, 小鸡, Drosophila melanogaster, Non-Human Primate
    宿主
    • 135
    • 89
    • 3
    小鼠
    克隆类型
    • 135
    • 91
    • 1
    单克隆
    标记
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    This PCNA antibody is un-conjugated
    应用范围
    • 187
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    The mouse monoclonal antibody PC10 (also known as 3F81) recognizes PCNA, a 36 kDa conserved nuclear protein serving as a cofactor for DNA synthesis.
    交叉反应 (详细)
    Human, Non-Human Primates, Mouse, Rat, Chicken, Drosophila
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    recombinant rat PCNA
    克隆位点
    PC10
    亚型
    IgG2a kappa
    Top Product
    Discover our top product PCNA Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    别名
    PCNA (PCNA 产品)
    背景
    Proliferating cell nuclear antigen,PCNA (proliferating cell nuclear antigen) is the DNA polymerase delta auxiliary protein acting in homotrimeric form to increase the processivity of leading strand synthesis during DNA replication. PCNA is expressed in the nucleus of all proliferating cells. In response to DNA damage, it is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. PCNA is a useful marker of DNA synthesis, as its form not involved in DNA synthesis degradates in histological preparations in the presence of organic solvents.,ATLD2
    基因ID
    5111
    UniProt
    P12004
    途径
    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
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