PCNA 抗体
Quick Overview for PCNA 抗体 (ABIN5633264)
抗原
See all PCNA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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    - 
                                            原理
- Anti-PCNA Purified
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                                            特异性
- The mouse monoclonal antibody PC10 (also known as 3F81) recognizes PCNA, a 36 kDa conserved nuclear protein serving as a cofactor for DNA synthesis.
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                                            交叉反应 (详细)
- Human, Non-Human Primates, Mouse, Rat, Chicken, Drosophila
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                                            纯化方法
- Purified by protein-A affinity chromatography.
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                                            纯度
- > 95 % (by SDS-PAGE)
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                                            免疫原
- recombinant rat PCNA
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                                            亚型
- IgG2a kappa
 
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                                            应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
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                                            限制
- 仅限研究用
 
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    - 
                                            浓度
- 1 mg/mL
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                                            缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C
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                                            储存方法
- Store at 2-8°C. Do not freeze.
 
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    - PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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                                            别名
- PCNA
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                                            背景
- Proliferating cell nuclear antigen,PCNA (proliferating cell nuclear antigen) is the DNA polymerase delta auxiliary protein acting in homotrimeric form to increase the processivity of leading strand synthesis during DNA replication. PCNA is expressed in the nucleus of all proliferating cells. In response to DNA damage, it is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. PCNA is a useful marker of DNA synthesis, as its form not involved in DNA synthesis degradates in histological preparations in the presence of organic solvents.,ATLD2
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                                            基因ID
- 5111
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                                            UniProt
- P12004
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                                            途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
 抗原
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