c-MET 抗体 (C-Term)
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Quick Overview for c-MET 抗体 (C-Term) (ABIN5611438)
抗原
See all c-MET (MET) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to Hepatocyte Growth Factor Receptor (MET).
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- MET antibody was raised against a synthetic peptide from C-terminus of human c-Met protein Genename: MET
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0,2 mg/mL
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缓冲液
- 10 mM PBS/1 % BSA buffer pH 7.4 with 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- c-MET (MET) (Met Proto-Oncogene (MET))
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别名
- HGF Receptor
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背景
- Met, an HGF Receptor/Met type protein kinase, is a cell-surface proto-oncogene that mediates the biological activities of hepatocyte growth factor. The protein is a disulfide-linked heterodimer comprised of two subunits: a 50 kD extracellular alpha subunit and a membrane-spanning 145 kD beta subunit that binds ligand. Met is an important regulator of cell proliferation and differentiation, organ regeneration, embryogenesis, and tumorogenesis. Constitutive activation mutations of the met gene lead to many cancers, particularly renal papillary carcinoma.Synonyms: HGF/SF receptor, Hepatocyte growth factor receptor, MET, Met proto-oncogene tyrosine kinase, Scatter factor receptor, c-Met
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基因ID
- 4233
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NCBI登录号
- NP_000236
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UniProt
- P08581
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途径
- RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
抗原
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