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KIR3DL1 抗体 (AA 22-340)

KIR3DL1 适用: 人, 大鼠 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6D9A4 unconjugated
产品编号 ABIN5611327
发货至: 中国
  • 抗原 See all KIR3DL1 抗体
    KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
    抗原表位
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-340
    适用
    • 46
    • 18
    • 17
    • 1
    人, 大鼠
    宿主
    • 46
    • 15
    小鼠
    克隆类型
    • 46
    • 15
    单克隆
    标记
    • 26
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIR3DL1 antibody is un-conjugated
    应用范围
    • 45
    • 16
    • 14
    • 12
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human KIR3DL1 (AA: extra 22-340) expressed in HEK293 cells.
    克隆位点
    6D9A4
    亚型
    IgG2b
    Top Product
    Discover our top product KIR3DL1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))
    别名
    KIR3DL1 (KIR3DL1 产品)
    别名
    KIR3DL1 antibody, KIR3DL3 antibody, CD158E1 antibody, KIR antibody, KIR3DL1/S1 antibody, NKAT3 antibody, NKB1 antibody, NKB1B antibody, Kirl1 antibody, Kirl2 antibody, Krl1 antibody, killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 antibody, uncharacterized LOC100437736 antibody, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 antibody, KIR3DL1 antibody, LOC100437736 antibody, Kir3dl1 antibody
    背景

    Description: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.

    Aliases: KIR, NKB1, NKAT3, NKB1B, NKAT-3, CD158E1, KIR3DL1/S1

    分子量
    49 kDa
    基因ID
    3811
    HGNC
    3811
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