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SLC7A8 抗体

SLC7A8 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5564261
发货至: 中国
  • 抗原 See all SLC7A8 抗体
    SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))
    适用
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 9
    • 4
    克隆类型
    • 9
    • 4
    多克隆
    标记
    • 13
    This SLC7A8 antibody is un-conjugated
    应用范围
    • 12
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Recognizes mouse and rat Slc7a8. Has been reported to work in human samples (Wirth,et al.; 2009), but was not tested in-house.Detects a -50kDa Slc7a8 band in wild type mouse brain, kidney, jejunum, ileum and othertissues, which is absent in knock-out animals. ln some tissues the antibody detects anadditional unknown 38kDa band.
    交叉反应 (详细)
    Other species not tested.Detects a ~50 kDa Slc7a8 band in wild type mouse brain, kidney, jejunum, ileum and other tissues, which is absent in knock-out animals. In some tissues the antibody detects an additional unknown 38 kDa band.
    纯化方法
    Antigen affinity purified.
    免疫原
    Synthetic peptide corresponding to a partial sequence of mouse Slc7a8 (Q9QXW9).
    Top Product
    Discover our top product SLC7A8 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 1 mg/mL BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • 抗原
    SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))
    别名
    Slc7a8 [Lat2] (SLC7A8 产品)
    别名
    LAT2 antibody, LPI-PC1 antibody, Lat2 antibody, Lat4 antibody, XAA2 antibody, lat2 antibody, lpi-pc1 antibody, 4F2LC-5 antibody, AA408822 antibody, si:ch211-14a17.3 antibody, si:zc14a17.3 antibody, slc7a8 antibody, solute carrier family 7 member 8 antibody, solute carrier family 7 member 8 L homeolog antibody, solute carrier family 7 (amino acid transporter, L-type), member 8 antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 antibody, solute carrier family 7 (amino acid transporter light chain, L system), member 8b antibody, SLC7A8 antibody, Slc7a8 antibody, slc7a8.L antibody, slc7a8 antibody, slc7a8b antibody
    背景
    L-type amino acid transporter (LAT) family members are Na(+)-independent transporters, which deliver neutral amino acids into cells. The four LATs, LAT1 (SLC7A5), LAT2 (SLC7A8), LAT3 (SLC43A1) and LAT4 (SLC43A2) are responsible for the majority of cellular leucine uptake. They show increased expression in many cancers and are critical for control of protein translation and cell growth through the mTORC1 pathway. The increased transporter expression observed in cancers is regulated by transcriptional pathways such as hormone receptors, c-myc and nutrient starvation responses.
    UniProt
    Q9QXW9
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