HES1 抗体
Quick Overview for HES1 抗体 (ABIN5564238)
抗原
See all HES1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Recognizes human, mouse and rat HES1.
-
交叉反应
- 人, 小鼠, 大鼠
-
纯度
- >95 % (SDS-PAGE)
-
免疫原
- Recombinant human Hes1 protein fused to a His-tag.
-
亚型
- IgG2b
-
-
anti-Hes Family bHLH Transcription Factor 1 (HES1) (N-Term) antibody
HES1 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 斑马鱼, 马 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 41-150) antibodyHES1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) antibodyHES1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 9-38) antibodyHES1 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 1-277) antibodyHES1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 24-35) antibodyHES1 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 马, 猴, Bat, 非洲爪蟾, Hamster WB, IHC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) antibodyHES1 适用: 人 ELISA, LMNX 宿主: 小鼠 Monoclonal OTI1B5 unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 21-251) antibodyHES1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (N-Term) antibodyHES1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) antibodyHES1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 7B9 unconjugated
-
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- HEPES with 0.15M NaCl, 0.01 % BSA, 0.03 % sodium azide, and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
-
-
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
-
别名
- Hairy and Enhancer of Split 1
-
背景
- The Notch signaling pathway is important for cell-cell communication, which involve gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. It critically influences cell proliferation, differentiation, and apoptosis in metazoans. The hairy and enhancer of split (HES) family is a basic helix-loop-helix (bHLH) type trancriptional repressor and acts as Notch effectors by negatively regulating expression of downstream target genes such as tissue-specific transcription factors. HES-1 is an upstream negative regulator of REST expression. Silencing of the transcriptional repressor REST is required for terminal differentiation of neuronal and beta-cells. Recent integrative genomic analyses on HES/HEY family suggest that HES1 and HES3 are target genes of the embryonic stem cell-specific network of transcription factors, and that HES1, HES5, HEY1, HEY2 and HEYL are target genes of Notch signaling pathway.
-
途径
- DNA Damage Repair
抗原
-
