Fibronectin 抗体
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- 抗原 See all Fibronectin 抗体
- Fibronectin
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适用
- 人, 小鼠, 大鼠, Pig, Cow, 小鸡, 犬, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Fibronectin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Functional Studies (Func)
- 特异性
- Recognizes an epitope located in the EDA sequence of human cellular fibronectin (FN).
- 交叉反应
- 小鸡, 牛, 犬, 人, 猴, 小鼠, 猪, 大鼠
- 无交叉反应
- 小鼠, 大鼠
- 交叉反应 （详细）
- Does not detect extracellular FN (plasma FN). Cross-reacts with mouse, rat, monkey, pig, dog, cow and chicken fibronectin EDA (according to literature). Cross-reacts with mouse, rat, monkey, pig, dog, cow and chicken fibronectin EDA (according to literature).
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.001EU/μg purified protein (LAL test, Lonza).
- 免疫原
- Recombinant Extra Domain A (EDA) region of human cellular fibronectin.
- 克隆位点
- IST-9
- 亚型
- IgG1
- Top Product
- Discover our top product Fibronectin Primary Antibody
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anti-Fibronectin (AA 1201-1300) antibody
适用: 人, 小鼠, 大鼠, Cow WB, ELISA, ICC, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Fibronectin antibody (Biotin)适用: 人, 小鼠, 大鼠, Cow, 猴 WB, IHC, IP, ELISA 宿主: 兔 Polyclonal Biotin
anti-Fibronectin (AA 2117-2236) antibody适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibronectin (AA 355-558) antibody适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibronectin antibody适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Fibronectin (AA 313-607) antibody适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibronectin (AA 1998-2106) antibody适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibronectin antibody适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibronectin antibody适用: 人 WB, IHC, IP, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibronectin (AA 2240-2280) antibody适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal 1B9 unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In 20 mM sodium phosphate buffer, pH 7.6 containing 150 mM sodium chloride.
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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- 抗原
- Fibronectin
- Abstract
- Fibronectin 产品
- 别名
- FN antibody, cig antibody, fibronectin antibody, finc antibody, lets antibody, msf antibody, CIG antibody, ED-B antibody, FINC antibody, FNZ antibody, GFND antibody, GFND2 antibody, LETS antibody, MSF antibody, E330027I09 antibody, Fn antibody, Fn-1 antibody, FIBNEC antibody, fn-1 antibody, fibronectin 1 antibody, FN1 antibody, fn1 antibody, Fn1 antibody
- 背景
- Fibronectin is a major component of the extracellular matrix that binds to integrins, cell surfaces and various compounds including collagen, fibrin, heparin, DNA and actin. It occurs in two main forms: plasma and cellular fibronectin. EDA (Extra Domain A)-containing cellular fibronectin (EDA-FN) plays a major role in cell adhesion, growth, migration and differentiation and it is important for processes such as wound healing and embryonic development. It is associated with fibroblast differentiation by increasing alpha-SMA expression, collagen deposition, cell contractility and focal adhesion kinase (FAK) activation. EDA-FN promotes cell spread by interacting with the integrins alpha5-beta1, alpha4-beta1 and alpha9-beta1 and has been shown to promote angiogenesis, lymphangiogenesis and metastasis of colorectal tumors. In transformed or tumor-derived cells the EDA segment is about 10-times higher than in fibronectin from normal fibroblasts and it may therefore be a significant marker for malignancy.
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