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DELE1/KIAA0141 抗体 (N-Term)

DELE1 适用: 人, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449949
发货至: 中国
  • 抗原 See all DELE1/KIAA0141 (DELE1) 抗体
    DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))
    抗原表位
    • 4
    • 2
    • 1
    N-Term
    适用
    • 8
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 6
    • 2
    克隆类型
    • 8
    多克隆
    标记
    • 8
    This DELE1/KIAA0141 antibody is un-conjugated
    应用范围
    • 8
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    18 amino acid synthetic peptide near the amino terminus of Human DELE
    亚型
    IgG
    Top Product
    Discover our top product DELE1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))
    别名
    KIAA0141 (DELE1 产品)
    别名
    KIAA0141 antibody, MGC139304 antibody, DELE antibody, 2700004E22Rik antibody, Dele antibody, Kiaa0141 antibody, KIAA0141 antibody, KIAA0141 ortholog antibody, RIKEN cDNA 0610009O20 gene antibody, SEL1 domain containing protein RGD735029 antibody, KIAA0141 antibody, 0610009O20Rik antibody, RGD735029 antibody
    背景
    DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-alpha and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-alpha, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.
    基因ID
    9812
    NCBI登录号
    NP_055588
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