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FBXO43 抗体 (C-Term)

FBXO43 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499984
发货至: 中国
  • 抗原 See all FBXO43 抗体
    FBXO43 (F-Box Protein 43 (FBXO43))
    抗原表位
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 10
    • 3
    • 2
    • 1
    宿主
    • 9
    • 2
    • 1
    克隆类型
    • 10
    • 2
    多克隆
    标记
    • 12
    This FBXO43 antibody is un-conjugated
    应用范围
    • 10
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    IL-1RAcP antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of IL-1RAcP, which differs from the sequence of mouse origin by three amino acids. It has no cross activity to other member in the IL-1 receptor family.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human IL-1RAcP (C-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product FBXO43 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1/500 to 1/1000. An approximately 66 kDa band can be detected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    FBXO43 (F-Box Protein 43 (FBXO43))
    别名
    FBXO43 (FBXO43 产品)
    别名
    EMI2 antibody, ERP1 antibody, FBX43 antibody, 4930533G20Rik antibody, Emi2 antibody, emi2 antibody, erp1 antibody, Xerp1 antibody, zgc:66488 antibody, F-box protein 43 antibody, F-box protein 43 L homeolog antibody, FBXO43 antibody, Fbxo43 antibody, fbxo43 antibody, fbxo43.L antibody
    背景
    The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I(IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1).IL-1 RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kappaB inducing kinae (NIK) and of NF-kappaB, recruites to the IL-1R complex through IL-1 RAcP(2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP(3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.Synonyms: EMI2, Endogenous meiotic inhibitor 2, F-box only protein 43, FBP5B
    基因ID
    100101275
    UniProt
    Q8AXF4
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