This antibody detects ZMYM3 at N-term. At least three isoforms of ZMYM3 are known to exist, this antibody will detect all three. ZMYM3 antibody is predicted to not cross-react with other ZMYM protein family members.
交叉反应 (详细)
Species reactivity (tested):Human, mouse
纯化方法
Affinity chromatography purified via peptide column
免疫原
20 amino acid peptide near the amino terminus of human AXIN2
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM3 is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X,13) involving this gene is associated with X-linked mental retardation.Synonyms: DXS6673E, KIAA0385, ZNF261, Zinc finger MYM-type protein 3, Zinc finger protein 261