TRAF2 抗体 (AA 39-188)
Quick Overview for TRAF2 抗体 (AA 39-188) (ABIN5542488)
抗原
See all TRAF2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 39-188
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原理
- TRAF2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human TRAF2 (AA: 39-188) expressed in E. Coli.
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亚型
- IgG1
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anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 1-300) antibody
TRAF2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 238-491) antibodyTRAF2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (C-Term) antibodyVerified TRAF2 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) antibodyTRAF2 适用: 人 WB, ELISA, IHC, IP, FACS 宿主: 兔 Monoclonal 9A5 unconjugated Recombinant Antibody
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 39-188) antibodyTRAF2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4A12D9 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 401-501) antibodyTRAF2 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 147-281) antibodyTRAF2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 1-501) antibodyTRAF2 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (C-Term) antibodyTRAF2 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 1-501) antibodyTRAF2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))
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别名
- TRAF2
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背景
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The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.
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分子量
- 55.8KD
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基因ID
- 7186
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UniProt
- Q12933
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response, S100 Proteins
抗原
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