TARDBP 抗体 (AA 126-260)
Quick Overview for TARDBP 抗体 (AA 126-260) (ABIN5542391)
抗原
See all TARDBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 126-260
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原理
- TARDBP Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human TARDBP (AA: 126-260) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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别名
- TARDBP
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背景
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HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
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分子量
- 44.7 kDa
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基因ID
- 23435
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UniProt
- Q13148
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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