EDNRB 抗体 (Extracellular Domain, N-Term)
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- 抗原 See all EDNRB 抗体
- EDNRB (Endothelin Receptor Type B (EDNRB))
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抗原表位
- Extracellular Domain, N-Term
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适用
- 人, 犬, 猴, 灵长类
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EDNRB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects N-terminal extracellular domain of Endothelin B Receptor (Family: GPCR Subfamily: Endothelin).
- 纯化方法
- Peptide Immunogen Affinity Chromatography
- 免疫原
- Synthetic 19 amino acid peptide from N-terminal extracellular domain of human EDNRB
- Top Product
- Discover our top product EDNRB Primary Antibody
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anti-Endothelin Receptor Type B (EDNRB) (AA 31-80) antibody
EDNRB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (AA 27-101) antibodyEDNRB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (C-Term) antibodyEDNRB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (AA 1-100) antibodyEDNRB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (N-Term) antibodyEDNRB 适用: 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (AA 409-439), (C-Term) antibodyEDNRB 适用: 人, 小鼠 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB19285 unconjugated
anti-Endothelin Receptor Type B (EDNRB) (AA 378-442) antibodyEDNRB 适用: 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) antibodyEDNRB 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Endothelin Receptor Type B (EDNRB) (AA 27-101) antibodyEDNRB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5H2 unconjugated
anti-Endothelin Receptor Type B (EDNRB) (N-Term) antibodyEDNRB 适用: 人, 犬 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Western Blot. Immunocytochemistry. Immunohistochemistry on Paraffin Embedded Sections : 4-11 μg/mL Antigen Retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.09 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20 to -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
- 有效期
- 12 months
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: "Endothelin B receptor expression correlates with tumour angiogenesis and prognosis in oesophageal squamous cell carcinoma." in: British journal of cancer, Vol. 110, Issue 4, pp. 1027-33, (2014) (PubMed).
: "The orphan G-protein coupled receptor RDC1: evidence for a role in chondrocyte hypertrophy and articular cartilage matrix turnover." in: Osteoarthritis and cartilage, Vol. 14, Issue 6, pp. 597-608, (2006) (PubMed).
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: "Endothelin B receptor expression correlates with tumour angiogenesis and prognosis in oesophageal squamous cell carcinoma." in: British journal of cancer, Vol. 110, Issue 4, pp. 1027-33, (2014) (PubMed).
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- 抗原
- EDNRB (Endothelin Receptor Type B (EDNRB))
- 别名
- endothelin b receptor (EDNRB 产品)
- 别名
- ABCDS antibody, ET-B antibody, ET-BR antibody, ETB antibody, ETBR antibody, ETRB antibody, HSCR antibody, HSCR2 antibody, WS4A antibody, Ednra antibody, Etb antibody, ETR-b antibody, ETb antibody, Sox10m1 antibody, EDNRB antibody, abcds antibody, etb antibody, etrb antibody, hscr antibody, hscr2 antibody, endothelin receptor type B antibody, EDNRB antibody, Ednrb antibody, ednrb antibody
- 背景
- The Endothelin Receptor ETB is expressed in most tissues. Mutations of the receptor gene are responsible for Hirschsprung disease type 2, a multigenic disorder with phenotypes such as bicolored irides, megacolon, hypopigmentation, and hearing loss. The ETB receptor has similar affinity for all three endothelins and activates a phosphatidylinositol-calcium second messenger system. A splice variant, termed SVR, has been described the sequence of the ETB-SVR receptor is identical to ET-B receptor, with the exception of the intracellular C-terminal domain. While both splice variants bind endothelin ET1, they exhibit different responses, which suggests that they may be functionally distinct. The endothelin B receptor has been reported to be expressed in adrenal, aorta, artery, brain, breast, eye, epididymis, ganglion, heart, kidney, liver, lung, ovary, placenta, prostate, skin, testis, uterus, and vessel.
- UniProt
- P24530
- 途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process
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