ICOSLG 抗体 (Extracellular Domain)
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Quick Overview for ICOSLG 抗体 (Extracellular Domain) (ABIN5541150)
抗原
See all ICOSLG 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- This antibody recognizes Human CD275 / ICOS Ligand. Other species not tested.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Genetic immunisation with cDNA encoding Human ICOSL (Extracellular Domain).
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亚型
- IgG1
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应用备注
- Flow Cytometry: 1.2 μg/10 6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered saline, pH 7.2
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
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别名
- cd275,icos ligand
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背景
- Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS)(1). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secre-tion (2,3).
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UniProt
- O75144
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途径
- Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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