This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This BLOC1S3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-202 amino acids from the C-terminal region of human BLOC1S3.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
BLOC1S3
(Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))
BLOS3 antibody, HPS8 antibody, RP antibody, BC043666 antibody, Blos3 antibody, E230011O18 antibody, rp antibody, biogenesis of lysosomal organelles complex 1 subunit 3 antibody, biogenesis of lysosomal organelles complex-1, subunit 3 antibody, BLOC1S3 antibody, Bloc1s3 antibody
背景
This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.