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PARP1 抗体 (N-Term)

This anti-PARP1 antibody is a 兔 多克隆 antibody detecting PARP1 in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN5535648
发货至: 中国

Quick Overview for PARP1 抗体 (N-Term) (ABIN5535648)

抗原

See all PARP1 抗体
PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PARP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
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    AA 183-214, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

    免疫原

    This PARP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-214 amino acids from the N-terminal region of human PARP1.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    For IF starting dilution is: 1:10~50

    For FACS starting dilution is: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

    别名

    PARP1

    背景

    PARP1 is a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

    分子量

    113 kDa

    基因ID

    142

    UniProt

    P09874

    途径

    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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