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IGF1 抗体 (N-Term)

Name: IGF1 抗体 (N-Term)
SKU: ABIN5534411
Availability: OutOfStock

IGF1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western blot analysis of IGF1R Antibody (N-term K66) in WiDr cell line lysates (35ug/lane)

IGF1R Antibody (N-term K66) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

IHC

Flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).

FACS

3 images

产品编号 ABIN5534411

发货至: 中国

Datasheet as PDF

抗原 See all IGF1 抗体

IGF1 (Insulin-Like Growth Factor 1 (IGF1))
抗原表位
18

15

15

9

8

4

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 51-77, N-Term
适用
149

69

60

22

16

9

7

3

2

1
人
宿主
127

50

10

2

1

1
兔
Compatible Secondaries
克隆类型
136

53
多克隆
标记
93

29

13

7

5

5

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This IGF1 antibody is un-conjugated
应用范围
143

76

66

55

41

30

27

26

26

20

15

13

9

8

8

7

7

6

4

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

免疫原

This IGF1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human IGF1R.

亚型

Ig Fraction

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anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-100) antibody
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anti-Insulin-Like Growth Factor 1 (IGF1) (AA 115-144), (C-Term) antibody
IGF1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33711 unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) antibody (HRP)
IGF1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP

应用备注

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

限制

仅限研究用
状态

Liquid

浓度

2 mg/mL

缓冲液

Supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

IGF1 (Insulin-Like Growth Factor 1 (IGF1))

别名

IGF1 (IGF1 产品)

别名

IGF-I antibody, IGF1A antibody, IGFI antibody, C730016P09Rik antibody, Igf-1 antibody, Igf-I antibody, Npt2B antibody, IGF-1 antibody, IGFIA antibody, IGF-IB antibody, igf1 antibody, IGF-1L antibody, IGF-1a antibody, IGF1 antibody, igf-1 antibody, igf1-A antibody, igf1.S antibody, xigf1 antibody, insulin like growth factor 1 antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I antibody, insulin like growth factor 1 L homeolog antibody, IGF1 antibody, Igf1 antibody, LOC100136741 antibody, igf1 antibody, LOC678666 antibody, igf1.L antibody, LOC104911603 antibody

背景

The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.

分子量

155 kDa

基因ID

3480

UniProt

P08069

途径

RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation