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EPS15 抗体 (N-Term)

EPS15 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5533566
发货至: 中国
  • 抗原 See all EPS15 抗体
    EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
    抗原表位
    • 15
    • 11
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 186-216, N-Term
    适用
    • 45
    • 15
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 45
    克隆类型
    • 45
    多克隆
    标记
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPS15 antibody is un-conjugated
    应用范围
    • 21
    • 14
    • 14
    • 13
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This EPS15R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-216 amino acids from the N-terminal region of human EPS15R.
    亚型
    Ig Fraction
    Top Product
    Discover our top product EPS15 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
    别名
    EPS15 (EPS15 产品)
    别名
    AF-1P antibody, AF1P antibody, MLLT5 antibody, CG16932 antibody, Dmel\\CG16932 antibody, EH1 antibody, EPS-15 antibody, Eps15 antibody, anon-WO0118547.85 antibody, eps-15 antibody, eps15 antibody, i31 antibody, 2410112D09Rik antibody, RGD1307641 antibody, epidermal growth factor receptor pathway substrate 15 antibody, Epidermal growth factor receptor pathway substrate clone 15 antibody, hypothetical protein antibody, EPS15 antibody, Eps-15 antibody, eps15 antibody, Eps15 antibody, PGTG_06574 antibody
    背景
    Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. The process of target selection, covalent attachment and shuttle to the 26S proteasome is a vital means of regulating the concentrations of key regulatory proteins in the cell by limiting their lifespans. Polyubiquitination is a common feature of this modification. Serial steps for modification include the activation of ubiquitin, an ATP-dependent formation of a thioester bond between ubiquitin and the enzyme E1, transfer by transacylation of ubiquitin from E1 to the ubiquitin conjugating enzyme E2, and covalent linkage to the target protein directly by E2 or via E3 ligase enzyme. Deubiquitination enzymes also exist to reverse the marking of protein substrates. Posttranslational tagging by Ub is involved in a multitude of cellular processes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, stress responses, the immune response, and nervous system functions.
    分子量
    94 kDa
    基因ID
    58513
    UniProt
    Q9UBC2
    途径
    EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation
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