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CERK 抗体 (C-Term)

CERK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5532853
发货至: 中国
  • 抗原 See all CERK 抗体
    CERK (Ceramide Kinase (CERK))
    抗原表位
    • 7
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 487-516, C-Term
    适用
    • 37
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 34
    • 3
    克隆类型
    • 37
    多克隆
    标记
    • 24
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CERK antibody is un-conjugated
    应用范围
    • 21
    • 14
    • 6
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This CERK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-516 amino acids from the C-terminal region of human CERK.
    亚型
    Ig Fraction
    Top Product
    Discover our top product CERK Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.9 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    CERK (Ceramide Kinase (CERK))
    别名
    CERK (CERK 产品)
    别名
    AI848610 antibody, D330016D08Rik antibody, mKIAA1646 antibody, LK4 antibody, dA59H18.2 antibody, dA59H18.3 antibody, hCERK antibody, CERK antibody, si:ch211-162i19.1 antibody, MGC81777 antibody, CG16708 antibody, DCERK antibody, Dcerk antibody, Dmel\\CG16708 antibody, dcerk antibody, ceramide kinase antibody, ceramide kinase S homeolog antibody, Ceramide kinase antibody, Cerk antibody, CERK antibody, cerk antibody, cerk.S antibody, CpipJ_CPIJ003342 antibody, LOAG_11245 antibody, LOC5579301 antibody, Bm1_50005 antibody
    背景
    Ceramide kinases convert the sphingolipid metabolite ceramide into ceramide-1-phosphate, both key mediators of cellular apoptosis and survival. Ceramide metabolism plays an essential role in the viability of neuronal cells, the membranes of which are particularly rich in sphingolipids. CERK catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. This enzyme acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8 dihydroceramide), and to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. High level expression is noted in heart, brain, skeletal muscle, kidney and liver, moderate expression in peripheral blood leukocytes and thymus, and low expression in spleen, small intestine, placenta and lung.
    分子量
    60 kDa
    基因ID
    64781
    UniProt
    Q8TCT0
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