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TRIB1 抗体 (C-Term)

TRIB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5532742
发货至: 中国
  • 抗原 See all TRIB1 抗体
    TRIB1 (Tribbles Homolog 1 (TRIB1))
    抗原表位
    • 15
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 341-370, C-Term
    适用
    • 51
    • 14
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 45
    • 4
    • 3
    克隆类型
    • 49
    • 3
    多克隆
    标记
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIB1 antibody is un-conjugated
    应用范围
    • 38
    • 22
    • 13
    • 13
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This TRIB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human TRIB1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product TRIB1 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    TRIB1 (Tribbles Homolog 1 (TRIB1))
    别名
    TRIB1 (TRIB1 产品)
    别名
    TRIB1 antibody, c8fw antibody, gig2 antibody, skip1 antibody, trb1 antibody, tribbles antibody, C8FW antibody, GIG2 antibody, SKIP1 antibody, TRB1 antibody, A530090O15Rik antibody, TRB-1 antibody, Trb1 antibody, Gig2 antibody, tribbles pseudokinase 1 antibody, tribbles pseudokinase 1 L homeolog antibody, tribbles homolog 1 (Drosophila) antibody, TRIB1 antibody, trib1 antibody, trib1.L antibody, Trib1 antibody
    背景
    TRIB1 antibody, also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1.
    分子量
    41 kDa
    基因ID
    10221
    UniProt
    Q96RU8
    途径
    Smooth Muscle Cell Migration
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