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HFE2 抗体 (C-Term)

HFE2 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5532574
发货至: 中国
  • 抗原 See all HFE2 抗体
    HFE2 (Hemochromatosis Type 2 (Juvenile) (HFE2))
    抗原表位
    • 15
    • 10
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 308-338, C-Term
    适用
    • 80
    • 23
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 72
    • 10
    克隆类型
    • 75
    • 7
    多克隆
    标记
    • 36
    • 9
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HFE2 antibody is un-conjugated
    应用范围
    • 75
    • 30
    • 27
    • 15
    • 13
    • 13
    • 9
    • 8
    • 8
    • 3
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This HFE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-338 amino acids from the C-terminal region of human HFE2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product HFE2 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For FACS starting dilution is: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    HFE2 (Hemochromatosis Type 2 (Juvenile) (HFE2))
    别名
    HFE2 (HFE2 产品)
    别名
    HFE2A antibody, HJV antibody, JH antibody, RGMC antibody, HFE2 antibody, DKFZp468F2322 antibody, 2310035L15Rik antibody, 5230400G09Rik antibody, AI414844 antibody, AI789733 antibody, DL-M antibody, Rgmc antibody, hemojuvelin antibody, RGMr antibody, hjv antibody, id:ibd3464 antibody, wu:fb38f10 antibody, zgc:136698 antibody, hemochromatosis type 2 (juvenile) antibody, hemochromatosis type 2 antibody, HFE2 antibody, Hfe2 antibody, hfe2 antibody
    背景
    HFE2 is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.
    分子量
    45 kDa
    基因ID
    148738
    UniProt
    Q6ZVN8
    途径
    Transition Metal Ion Homeostasis
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