This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This RASAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the Central region of human RASAL1.
RASAL1
适用: 大鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 680
应用备注
For WB starting dilution is: 1:1000
限制
仅限研究用
状态
Liquid
浓度
0.5 mg/mL
缓冲液
Supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
RASAL1
(RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
RASAL1 antibody, rasal1 antibody, MGC79606 antibody, RASAL antibody, MRASAL antibody, RAS protein activator like 1 antibody, RAS protein activator like 1 (GAP1 like) antibody, RASAL1 antibody, rasal1 antibody, Rasal1 antibody
背景
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described