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DUSP14 抗体 (C-Term)

DUSP14 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5531046
发货至: 中国
  • 抗原 See all DUSP14 抗体
    DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))
    抗原表位
    • 12
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    AA 168-198, C-Term
    适用
    • 53
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 46
    • 6
    • 1
    克隆类型
    • 49
    • 4
    多克隆
    标记
    • 26
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP14 antibody is un-conjugated
    应用范围
    • 41
    • 35
    • 22
    • 5
    • 5
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This DUSP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from the C-terminal region of human DUSP14.
    亚型
    Ig Fraction
    Top Product
    Discover our top product DUSP14 Primary Antibody
  • 应用备注
    For IHC-P starting dilution is: 1:50~100

    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))
    别名
    DUSP14 (DUSP14 产品)
    别名
    MGC84083 antibody, zgc:101746 antibody, DUSP14 antibody, mkp-l antibody, mkp6 antibody, MKP-L antibody, MKP6 antibody, 1110014C10Rik antibody, 2310042C07Rik antibody, D11Ertd395e antibody, Mkp6 antibody, dual specificity phosphatase 14 antibody, dual specificity phosphatase 14 L homeolog antibody, DUSP14 antibody, dusp14.L antibody, dusp14 antibody, Dusp14 antibody
    背景
    DUSP14 is involved in the inactivation of MAP kinases. This proein dephosphorylates ERK, JNK and p38 MAP-kinases. In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28, which interacts with B7-1 (CD80) and B7-2 (CD86) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK and JNK, and the subsequent creation of AP1 transcription factor. DUSP14 is a negative regulator of CD28 signaling.
    分子量
    22 kDa
    基因ID
    11072
    UniProt
    O95147
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