Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
纯化方法
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
免疫原
This Bmp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-986 amino acids from the C-terminal region of human Bmp1.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
OI13 antibody, PCOLC antibody, PCP antibody, PCP2 antibody, TLD antibody, Pcp antibody, Tld antibody, BMP1 antibody, submp antibody, tld antibody, xtld antibody, bmp-1 antibody, pcolc antibody, xbmp1 antibody, tolloid antibody, BMP-1 antibody, bmp1 antibody, bmp1a antibody, bone morphogenetic protein 1 antibody, Bone morphogenetic protein 1 antibody, bone morphogenetic protein 1 S homeolog antibody, bone morphogenetic protein 1, like antibody, BMP1 antibody, Bmp1 antibody, bmp1 antibody, bmp1.S antibody, bmp1l antibody
背景
The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.