-
- 抗原 See all MAP2K6 抗体
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
-
抗原表位
- AA 280-334
-
适用
- 人, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MAP2K6 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Anti-MEK6/MAP2K6 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-MEK6/MAP2K6 Antibody Picoband® (ABIN5518934). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human MEK6 recombinant protein (Position: A280-D334). Human MEK6 shares 92.7% amino acid (aa) sequence identity with mouse MEK6.
- 亚型
- IgG
- Top Product
- Discover our top product MAP2K6 Primary Antibody
-
anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 46-306) antibody
MAP2K6 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) antibodyMAP2K6 适用: 人, 小鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3H12C8 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 231-334) antibodyMAP2K6 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) antibodyMAP2K6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3H12B9 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (pSer207) antibodyMAP2K6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (pSer189), (pSer207) antibodyMAP2K6 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 1-334) antibodyMAP2K6 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) antibodyMAP2K6 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (N-Term) antibodyMAP2K6 适用: 人, 小鼠, 大鼠, Cow, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Han, J., Lee, J.-D., Jiang, Y., Li, Z., Feng, L., Ulevitch, R. J. Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J. Biol. Chem. 271: 2886-2891, 1996. 2. Mao, Z., Bonni, A., Xia, F., Nadal-Vicans, M., Greenberg, M. E. Neuronal activity-dependent cell survival mediated by transcription factor MEF2. Science 286: 785-790, 1999. 3. Mukherjee, S., Keitany, G., Li, Y., Wang, Y., Ball, H. L., Goldsmith, E. J., Orth, K. Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. Science 312: 1211-1214, 2006. - 说明
-
We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
- 抗原
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
- 别名
- MAP2K6 (MAP2K6 产品)
- 背景
-
Synonyms: Dual specificity mitogen-activated protein kinase kinase 6,MAP kinase kinase 6,MAPKK 6,2.7.12.2,MAPK/ERK kinase 6,MEK 6,Stress-activated protein kinase kinase 3,SAPK kinase 3,SAPKK-3,SAPKK3,MAP2K6,MEK6, MKK6, PRKMK6, SKK3,
Tissue Specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas. .
Background: MAP2K6 (Mitogen-activated protein kinase kinase 6), also known as MAP kinase kinase 6 (MAPKK 6) or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene. It is located on chromosome 17. MAPKK 6 is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediatedsignal transduction pathway, this gene is involved in many cellular processes such as stress-induced cell cycle arrest, transcription activation and apoptosis.
- 分子量
- 38 kDa
- 基因ID
- 5608
- UniProt
- P52564
- 途径
- MAPK Pathway, TLR signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
-
You are here:
