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Cytochrome C 抗体 (AA 2-105)

Name: Cytochrome C 抗体 (AA 2-105)
SKU: ABIN5518904
Availability: OutOfStock

CYCS 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

IHC analysis of Cytochrome C using anti-Cytochrome C antibody . (Cytochrome C 抗体 (AA 2-105))

IHC

Western blot analysis of Cytochrome C using anti-Cytochrome C antibody . (Cytochrome C 抗体 (AA 2-105))

IHC

5 images

(11 references)

产品编号 ABIN5518904

发货至: 中国

Datasheet as PDF

抗原 See all Cytochrome C (CYCS) 抗体

Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
抗原表位
15

13

9

5

5

5

4

4

2

2

2

2

2

1

1

1

1

1

1

1
AA 2-105
适用
138

107

89

38

24

22

21

18

17

16

3

3

2

2

2

1

1
人, 大鼠, 小鼠
宿主
85

65

5

1
兔
Compatible Secondaries
克隆类型
80

75

1
多克隆
标记
89

11

6

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This Cytochrome C antibody is un-conjugated
应用范围
119

48

41

36

33

26

23

22

14

13

13

12

3

3

3

3

2

2

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

原理

Anti-Cytochrome C/Cycs Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Cytochrome C/Cycs Antibody Picoband® (ABIN5518904). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived mouse Cytochrome C recombinant protein (Position: G2-E105). Mouse Cytochrome C shares 91.3% and 100% amino acid (aa) sequence identity with human and rat Cytochrome C, respectively.

亚型

IgG

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CYCS 适用: 人, 大鼠, 小鼠, 兔, 小鸡 WB, ELISA, FACS, IHC (p), ICC, IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 1-105) antibody
CYCS 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 5-100) antibody
CYCS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 13-99) antibody
CYCS 适用: 大鼠, 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 5-100) antibody
CYCS 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 1-105) antibody
CYCS 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5E6B11 unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 2-105) antibody
CYCS 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 91-105), (C-Term) antibody
CYCS 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) antibody
CYCS 适用: 人, 大鼠, 小鼠, 马, 犬, Pigeon, Drosophila melanogaster, Frog IHC, StM 宿主: 兔 Monoclonal CYCS-3128R unconjugated Recombinant Antibody

anti-Cytochrome C, Somatic (CYCS) antibody
CYCS 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat1. García-Heredia JM, et al. Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome. FEBS Lett, 2012 Jan 20. 2. Rajagopal BS, et al. The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant. Biochem J, 2013 Dec 15. 3. Simon M, et al. Versatility of non-native forms of human cytochrome c: pH and micellar concentration dependence. J Biol Inorg Chem, 2013 Jan.

说明

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Bai, Yang, Luo: "Effects of 5-hydroxy-4'-nitro-7-propionyloxy-genistein on inhibiting proliferation and invasion via activating reactive oxygen species in human ovarian cancer A2780/DDP cells." in: Oncology letters, Vol. 15, Issue 4, pp. 5227-5235, (2018) (PubMed).

Jiao, Ma, Wang, Li, Shan, Sun, Chen: "Methacryloxylethyl Cetyl Ammonium Chloride Induces DNA Damage and Apoptosis in Human Dental Pulp Cells via Generation of Oxidative Stress." in: International journal of biological sciences, Vol. 12, Issue 5, pp. 580-93, (2017) (PubMed).

Hu, Sun, Zhang, Zhang, Hu: "Catalpol inhibits apoptosis in hydrogen peroxide-induced cardiac myocytes through a mitochondrial-dependent caspase pathway." in: Bioscience reports, Vol. 36, Issue 3, (2017) (PubMed).

You, Li, Jin, Zheng, Chen, Yang: "Genistein protects against Aβ25-35 induced apoptosis of PC12 cells through JNK signaling and modulation of Bcl-2 family messengers." in: BMC neuroscience, Vol. 18, Issue 1, pp. 12, (2017) (PubMed).

Gan, Liu, Cao, Zhang, Sun: "FABP4 reversed the regulation of leptin on mitochondrial fatty acid oxidation in mice adipocytes." in: Scientific reports, Vol. 5, pp. 13588, (2016) (PubMed).

Han, Liu, Li, Tian, Han, Wang, Fu, Guo, Zhu, Du, Tian: "HOXB1 Is a Tumor Suppressor Gene Regulated by miR-3175 in Glioma." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142387, (2016) (PubMed).

Jiao, Ma, Wang, Li, Shan, Liu, Liu, Song, Yu, Yu, Liu, Huang, Chen: "N-Acetyl Cysteine Depletes Reactive Oxygen Species and Prevents Dental Monomer-Induced Intrinsic Mitochondrial Apoptosis In Vitro in Human Dental Pulp Cells." in: PLoS ONE, Vol. 11, Issue 1, pp. e0147858, (2016) (PubMed).

Ji, Geng, Zhou, Wei, Chen: "Chinese herbal medicine Yougui Pill reduces exogenous glucocorticoid-induced apoptosis in anterior pituitary cells." in: Neural regeneration research, Vol. 11, Issue 12, pp. 1962-1968, (2016) (PubMed).

Xu, Liu, Zhang, Wang, Wang, Yang, Huo, Sun: "Apoptosis-related protein expression in rabbits with blast brain injury following early hyperbaric oxygen therapy." in: Neural regeneration research, Vol. 7, Issue 17, pp. 1318-24, (2015) (PubMed).

Mo, Chen, Huang, Zhang, Li, Zhou: "Neuroprotective effect of tea polyphenols on oxyhemoglobin induced subarachnoid hemorrhage in mice." in: Oxidative medicine and cellular longevity, Vol. 2013, pp. 743938, (2014) (PubMed).

Song, Yue, Li, Li, Zhao, Zhang: "Study of the mechanism of sonodynamic therapy in a rat glioma model." in: OncoTargets and therapy, Vol. 7, pp. 1801-10, (2014) (PubMed).
抗原

Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

别名

Cycs (CYCS 产品)

背景

Synonyms: Cytochrome c, somatic,Cycs,
Tissue Specificity: Found in embryos and in adult liver and heart.
Background: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

分子量

14 kDa

基因ID

13063

UniProt

P62897

途径

Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity