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GJC1 抗体 (N-Term)

GJC1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518838
发货至: 中国
  • 抗原 See all GJC1 抗体
    GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))
    抗原表位
    • 12
    • 9
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 91-131, N-Term
    适用
    • 52
    • 29
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 51
    • 3
    克隆类型
    • 52
    • 2
    多克隆
    标记
    • 31
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GJC1 antibody is un-conjugated
    应用范围
    • 48
    • 27
    • 18
    • 16
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Gap junction gamma-1 protein(GJC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    YLGYAIHKIA KMEHGEADKK AARSKPYAMR WKQHRALEET E
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Gap junction gamma-1 protein(GJC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: gap junction protein, gamma 1
    Protein Name: Gap junction gamma-1 protein
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human Connexin 45/GJA7 (91-131aa YLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETE), identical to the related mouse and rat sequences.
    亚型
    IgG
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Zeng, Li, Li, Li, Xiao, Chu, Yang: "Effect of Novel Gasotransmitter hydrogen sulfide on renal fibrosis and connexins expression in diabetic rats." in: Bioengineered, Vol. 7, Issue 5, pp. 314-320, (2017) (PubMed).

  • 抗原
    GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))
    别名
    GJC1 (GJC1 产品)
    别名
    CX45 antibody, GJA7 antibody, cx45 antibody, gja7 antibody, MGC52735 antibody, GJD3 antibody, GJC1 antibody, C130009G16Rik antibody, Cnx45 antibody, Cx45 antibody, Gja-7 antibody, Gja7 antibody, gap junction protein gamma 1 antibody, gap junction protein gamma 1 L homeolog antibody, gap junction protein, delta 3, 31.9kDa antibody, gap junction protein, gamma 1 antibody, Gap junction gamma-1 protein antibody, GJC1 antibody, gjc1.L antibody, GJD3 antibody, Gjc1 antibody, gjc1 antibody
    背景
    Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) or connexin 45 (Cx45), is a protein that in humans is encoded by the GJC1 gene. The International Radiation Hybrid Mapping Consortium mapped the GJA7 gene to chromosome 17q21.31. This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell.

    Synonyms: Gap junction gamma-1 protein | Connexin-45 | Cx45 | Gap junction alpha-7 protein | GJC1 | GJA7 | P36383
    基因ID
    10052
    UniProt
    P36383
    途径
    Cell-Cell Junction Organization
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