BCL2L1 抗体 (AA 1-219)
(4 references)Quick Overview for BCL2L1 抗体 (AA 1-219) (ABIN5518741)
抗原
See all BCL2L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-219
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原理
- Anti-Bcl-XL/BCL2L1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Bcl-XL/BCL2L1 Antibody Picoband® (ABIN5518741). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Bcl-XL recombinant protein (Position: M1-T219). Human Bcl-XL shares 97.9% amino acid (aa) sequence identity with both mouse and rat Bcl-XL.
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亚型
- IgG
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anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibody
BCL2L1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E2-2A5 unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-120) antibodyBCL2L1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) antibodyBCL2L1 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibodyBCL2L1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibodyBCL2L1 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 81-200) antibodyBCL2L1 适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (AA 1-209) antibodyBCL2L1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 1 (BCL2L1) (N-Term) antibodyBCL2L1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: BCL2L1 BCL2-like 1". 2. Boise LH, González-García M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nuñez G, Thompson CB (Aug 1993). "bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death". Cell 74(4): 597-608. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Active targeting co-delivery system based on hollow mesoporous silica nanoparticles for antitumor therapy in ovarian cancer stem-like cells." in: Oncology reports, Vol. 38, Issue 3, pp. 1442-1450, (2018) (PubMed).
: "Emodin alleviates severe acute pancreatitis-associated acute lung injury by decreasing pre-B-cell colony-enhancing factor expression and promoting polymorphonuclear neutrophil apoptosis." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 5121-5128, (2018) (PubMed).
: "Grape Seed Proanthocyanidin Extract Prevents Ovarian Aging by Inhibiting Oxidative Stress in the Hens." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 9390810, (2018) (PubMed).
: "Azithromycin synergistically enhances anti-proliferative activity of vincristine in cervical and gastric cancer cells." in: Cancers, Vol. 4, Issue 4, pp. 1318-32, (2013) (PubMed).
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: "Active targeting co-delivery system based on hollow mesoporous silica nanoparticles for antitumor therapy in ovarian cancer stem-like cells." in: Oncology reports, Vol. 38, Issue 3, pp. 1442-1450, (2018) (PubMed).
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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别名
- BCL2L1
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背景
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Synonyms: Bcl-2-like protein 1,Bcl2-L-1,Apoptosis regulator Bcl-X,BCL2L1,BCL2L, BCLX,
Tissue Specificity: Bcl-X (S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X (L) is found in tissues containing long-lived postmitotic cells, such as adult brain.
Background: Bcl-2-like protein 1, also known as Bcl-XL, is a protein that in humans is encoded by the BCL2L1 gene. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform (Bcl-xL) acts as an apoptotic inhibitor and the shorter form (Bcl-xS) acts as an apoptotic activator.
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分子量
- 30 kDa
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基因ID
- 598
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UniProt
- Q07817
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途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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