SPAM1 抗体 (Middle Region)
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- 抗原 See all SPAM1 抗体
- SPAM1 (Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPAM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QQQNVQLSLT EATEKAKQEF EKAGKDFLVE TIKLGKLLRP NHLWGYYLFP
- 产品特性
- This is a rabbit polyclonal antibody against SPAM1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human SPAM1
- Top Product
- Discover our top product SPAM1 Primary Antibody
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anti-Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 100-300) antibody
SPAM1 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (Internal Region) antibodySPAM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) (AA 346-445) antibodySPAM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) antibodySPAM1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1) antibodySPAM1 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SPAM1 (Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1))
- 别名
- SPAM1 (SPAM1 产品)
- 别名
- AV039194 antibody, Ph-20 antibody, PH-20 antibody, PH20 antibody, HYA1 antibody, HYAL1 antibody, HYAL3 antibody, HYAL5 antibody, SPAG15 antibody, Spam antibody, XEH1 antibody, spam1 antibody, im:6902904 antibody, zgc:158668 antibody, sperm adhesion molecule 1 antibody, sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L homeolog antibody, sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) antibody, Spam1 antibody, SPAM1 antibody, spam1.L antibody, spam1 antibody
- 背景
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Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1, another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: SPAM1, HYAL3, PH20,
Protein Size: 509 - 基因ID
- 6677
- NCBI登录号
- NP_694859
- UniProt
- P38567
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