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MBTPS2 抗体 (N-Term)

MBTPS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5517527
发货至: 中国
  • 抗原 See all MBTPS2 抗体
    MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))
    抗原表位
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 29
    • 4
    • 3
    • 1
    宿主
    • 27
    • 2
    克隆类型
    • 27
    • 2
    多克隆
    标记
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBTPS2 antibody is un-conjugated
    应用范围
    • 19
    • 18
    • 14
    • 4
    • 3
    • 1
    Western Blotting (WB)
    序列
    VGGWTVVYLT DLVLKSSVYF KHSYEDWLEN NGLSISPFHI RWQTAVFNRA
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human MBTPS2
    Top Product
    Discover our top product MBTPS2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))
    别名
    MBTPS2 (MBTPS2 产品)
    别名
    BRESEK antibody, IFAP antibody, KFSDX antibody, S2P antibody, 9630032G22Rik antibody, AI662535 antibody, LRRGT00063 antibody, membrane bound transcription factor peptidase, site 2 antibody, membrane-bound transcription factor peptidase, site 2 antibody, MBTPS2 antibody, Mbtps2 antibody
    背景
    This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome), IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.

    Alias Symbols: S2P, IFAP, KFSD, KFSDX, OLMSX, BRESEK

    Protein Interaction Partner: UBC, ATF6B,

    Protein Size: 519
    基因ID
    51360
    NCBI登录号
    NM_015884, NP_056968
    UniProt
    O43462
    途径
    ER-Nucleus Signaling
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