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USP19 抗体 (Middle Region)

USP19 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5516193
发货至: 中国
  • 抗原 See all USP19 抗体
    USP19 (Ubiquitin Specific Peptidase 19 (USP19))
    抗原表位
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 35
    • 15
    • 9
    • 2
    • 1
    宿主
    • 32
    • 2
    • 1
    克隆类型
    • 35
    多克隆
    标记
    • 23
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP19 antibody is un-conjugated
    应用范围
    • 25
    • 13
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    SQFTGYAQHD AQEFMAFLLD GLHEDLNRIQ NKPYTETVDS DGRPDEVVAE
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human USP19
    Top Product
    Discover our top product USP19 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    USP19 (Ubiquitin Specific Peptidase 19 (USP19))
    别名
    USP19 (USP19 产品)
    别名
    wu:fc26a05 antibody, si:dkey-32e6.9 antibody, USP19 antibody, MGC145127 antibody, ZMYND9 antibody, 8430421I07Rik antibody, AI047774 antibody, Zmynd9 antibody, ubiquitin specific peptidase 19 antibody, universal stress protein antibody, ubiquitin carboxyl-terminal hydrolase 19 antibody, usp19 antibody, USP19 antibody, RR_RS18085 antibody, PTRG_09611 antibody, Usp19 antibody
    背景
    Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.

    Alias Symbols: ZMYND9

    Protein Size: 1419
    基因ID
    10869
    NCBI登录号
    NM_001199160, NP_001186089
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