MAP2K7 抗体 (N-Term)
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Quick Overview for MAP2K7 抗体 (N-Term) (ABIN5516106)
抗原
See all MAP2K7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LNLDISPQRP RPTLQLPLAN DGGSRSPSSE SSPQHPTPPA RPRHMLGLPS
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP2K7
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
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别名
- MAP2K7
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背景
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The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.
Alias Symbols: MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4
Protein Size: 462 -
基因ID
- 5609
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NCBI登录号
- NM_001297555, NP_660186
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途径
- MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
抗原
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