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MAP2K4 抗体 (C-Term)

This anti-MAP2K4 antibody is a 兔 多克隆 antibody detecting MAP2K4 in WB. Suitable for 人.
产品编号 ABIN5516102
发货至: 中国

Quick Overview for MAP2K4 抗体 (C-Term) (ABIN5516102)

抗原

See all MAP2K4 抗体
MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

适用

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宿主

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克隆类型

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多克隆

标记

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This MAP2K4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    NLKIIHRDIK PSNILLDRSG NIKLCDFGIS GQLVDSIAKT RDAGCRPYMA

    产品特性

    This is a rabbit polyclonal antibody against MAP2K4. It was validated on Western Blot.

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human MAP2K4
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

    别名

    MAP2K4

    背景

    This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.

    Alias Symbols: JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1

    Protein Interaction Partner: UBC, EGFR, GEMIN5, MAP3K5, MAP3K1, GCH1, MAPK10, MAPK9, MAPK8, MAPK1, ARRB2, ARRB1, MAP3K7, RBBP8, JUN, MAP2K7, APP, MAP3K2, MAPK14, AKT1, LRRK2, MAP2K4, MAP2K6, MAP3K4, MAP3K3, PML, BLNK, ITCH, MAPK8IP3, ZAK, SPAG9, TRIB1, MAP3K14, CFLAR, MAPK12, EFNA4,

    Protein Size: 399

    基因ID

    6416

    NCBI登录号

    NM_003010, NP_003001

    UniProt

    P45985

    途径

    MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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