IL1A 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for IL1A 抗体 (N-Term) (ABIN5515428)
抗原
See all IL1A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- IL1A Antibody - N-terminal region
-
序列
- VPDMFEDLKN CYSENEEDSS SIDHLSLNQK SFYHVSYGPL HEGCMDQSVS
-
预测反应
- Goat: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 83%
-
产品特性
- This is a rabbit polyclonal antibody against IL1A. It was validated on Western Blot.
-
纯化方法
- Affinity purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human IL1A
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54321-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- IL1A (Interleukin 1 alpha (IL1A))
-
别名
- IL1A
-
背景
-
Background Information: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Gene Name: interleukin 1, alpha
Alternative Symbols: IL1, IL-1A, IL1F1, IL1-ALPHA, IL-1 alpha
Protein Name: Interleukin-1 alpha
-
分子量
- 29kDa
-
基因ID
- 3552
-
NCBI登录号
- NP_000566
-
UniProt
- P01583
-
途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
-