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UNC13B 抗体 (Middle Region)

UNC13B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5515349
发货至: 中国
  • 抗原 See all UNC13B 抗体
    UNC13B (Unc-13 Homolog B (UNC13B))
    抗原表位
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 32
    • 18
    • 2
    宿主
    • 41
    • 2
    • 1
    克隆类型
    • 43
    • 1
    多克隆
    标记
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UNC13B antibody is un-conjugated
    应用范围
    • 32
    • 26
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    SYDLDYPERR AISPTSSSRY GSSCNVSQGS SQLSELDQYH EQDDDHRETD
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human UNC13B
    Top Product
    Discover our top product UNC13B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    UNC13B (Unc-13 Homolog B (UNC13B))
    别名
    UNC13B (UNC13B 产品)
    别名
    MUNC13 antibody, UNC13 antibody, Unc13h2 antibody, UNC13B antibody, Munc13-2 antibody, Munc13-1 antibody, Unc13a antibody, Unc13h1 antibody, unc-13 homolog B antibody, unc-13 homolog B (C. elegans) antibody, UNC13B antibody, Unc13b antibody
    背景
    This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.

    Alias Symbols: UNC13, MUNC13, Unc13h2

    Protein Size: 1591
    基因ID
    10497
    NCBI登录号
    NM_006377, NP_006368
    UniProt
    O14795
    途径
    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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