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UNC13B 抗体 (Middle Region)
UNC13B
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
UNC13B抗体详情
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抗原
See all UNC13B 抗体
UNC13B
(Unc-13 Homolog B (UNC13B))
抗原表位
All epitopes for UNC13B 抗体
Middle Region
适用
All reactivities for UNC13B 抗体
人
宿主
All hosts for UNC13B 抗体
兔
克隆类型
All clonalities for UNC13B 抗体
多克隆
标记
All conjugates for UNC13B 抗体
This UNC13B antibody is un-conjugated
应用范围
All applications for UNC13B 抗体
Western Blotting (WB)
序列
SYDLDYPERR AISPTSSSRY GSSCNVSQGS SQLSELDQYH EQDDDHRETD
纯化方法
Affinity purified
免疫原
The immunogen is a synthetic peptide directed towards the middle region of human UNC13B
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
UNC13B目标详情
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抗原
UNC13B
(Unc-13 Homolog B (UNC13B))
别名
UNC13B (UNC13B 产品 )
别名
MUNC13 antibody, UNC13 antibody, Unc13h2 antibody, UNC13B antibody, Munc13-2 antibody, Munc13-1 antibody, Unc13a antibody, Unc13h1 antibody, unc-13 homolog B antibody, unc-13 homolog B (C. elegans) antibody, UNC13B antibody, Unc13b antibody
背景
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. Alias Symbols: UNC13, MUNC13, Unc13h2 Protein Size: 1591
基因ID
10497
NCBI登录号
NM_006377 , NP_006368
UniProt
O14795
途径
Skeletal Muscle Fiber Development , Synaptic Vesicle Exocytosis
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