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RBM25 抗体 (Middle Region)

RBM25 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5515107
发货至: 中国
  • 抗原 See all RBM25 抗体
    RBM25 (RNA Binding Motif Protein 25 (RBM25))
    抗原表位
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 22
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 24
    克隆类型
    • 24
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RBM25 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    DRDRTKERDR DRDRERDRDR DRERSSDRNK DRSRSREKSR DRERERERER
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human RBM25
    Top Product
    Discover our top product RBM25 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RBM25 (RNA Binding Motif Protein 25 (RBM25))
    别名
    RBM25 (RBM25 产品)
    别名
    fi03e10 antibody, zgc:56208 antibody, wu:fi03e10 antibody, si:ch211-105d18.5 antibody, rnpc7 antibody, s164 antibody, NET52 antibody, RED120 antibody, RNPC7 antibody, S164 antibody, Snu71 antibody, fSAP94 antibody, 2600011C06Rik antibody, 2610015J01Rik antibody, A130095G20Rik antibody, AI159652 antibody, AL023075 antibody, AU043498 antibody, RNA binding motif protein 25b antibody, RNA binding motif protein 25 antibody, RNA binding motif protein 25 S homeolog antibody, putative rna binding motif protein 25 antibody, rbm25b antibody, Rbm25 antibody, rbm25.S antibody, rbm25 antibody, RBM25 antibody, Smp_078610 antibody
    背景
    RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.

    Alias Symbols: S164, NET52, RNPC7, Snu71, RED120, fSAP94

    Protein Size: 843
    基因ID
    58517
    NCBI登录号
    NM_021239, NP_067062
    UniProt
    P49756
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