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Lamin A/C 抗体 (C-Term)

Name: Lamin A/C 抗体 (C-Term)
SKU: ABIN5514925
Availability: OutOfStock

LMNA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

产品编号 ABIN5514925

发货至: 中国

Datasheet as PDF

抗原 See all Lamin A/C (LMNA) 抗体

Lamin A/C (LMNA)
抗原表位
10

8

8

8

7

7

6

6

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
139

82

77

26

15

13

8

7

6

6

6

4

4

3

3

2

2

1

1

1

1

1

1
人
宿主
105

42

3

1
兔
Compatible Secondaries
克隆类型
107

44
多克隆
标记
108

10

9

8

3

3

2

2

1

1

1

1

1

1
This Lamin A/C antibody is un-conjugated
应用范围
120

55

52

46

31

27

27

18

12

7

3

2

2

1

1
Western Blotting (WB)

序列

RTSGRVAVEE VDEEGKFVRL RNKSNEDQSM GNWQIKRQNG DDPLLTYRFP

产品特性

This is a rabbit polyclonal antibody against LMNA. It was validated on Western Blot.

纯化方法

Affinity purified

免疫原

The immunogen is a synthetic peptide directed towards the C-terminal region of Human LMNA

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anti-Lamin A/C (LMNA) antibody
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anti-Lamin A/C (LMNA) (pSer392) antibody
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anti-Lamin A/C (LMNA) antibody
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anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人 IHC, ELISA, IF, IP, FACS 宿主: 兔 Monoclonal 4H7 unconjugated Recombinant Antibody

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4-00E-07 unconjugated

anti-Lamin A/C (LMNA) (AA 481-646) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (AA 455-469) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC, ICC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 133A2 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

Lamin A/C (LMNA)

别名

LMNA (LMNA 产品)

别名

CDCD1 antibody, CDDC antibody, CMD1A antibody, CMT2B1 antibody, EMD2 antibody, FPL antibody, FPLD antibody, FPLD2 antibody, HGPS antibody, IDC antibody, LDP1 antibody, LFP antibody, LGMD1B antibody, LMN1 antibody, LMNC antibody, LMNL1 antibody, PRO1 antibody, Dhe antibody, 2459 antibody, 74/76 antibody, CG6944 antibody, D5 antibody, DM[[O]] antibody, Dm antibody, Dm(0) antibody, Dm0 antibody, Dm1 antibody, Dm2 antibody, DmLamin antibody, DmO antibody, Dm[[0]] antibody, Dm[[1]] antibody, Dm[[2]] antibody, Dm[[mit]] antibody, Dm[[o]] antibody, Dmel\\CG6944 antibody, Dmo antibody, LAM antibody, Lam Dm[[0]] antibody, Lam(Dm0) antibody, LamDm[[0]] antibody, LamDm[[o]] antibody, Lam[[Dm0]] antibody, Lamin Dm[[0]] antibody, jf27 antibody, l(2)04643 antibody, l(2)25Ec antibody, l(2)gdh-7 antibody, l(2)gdh7 antibody, l(2)jf27 antibody, lam antibody, lamDm0 antibody, lamDm[[0]] antibody, lamin antibody, lamin Dm0 antibody, lamin Dm[[0]] antibody, misg antibody, nlam antibody, cb948 antibody, fk66d12 antibody, wu:fk66d12 antibody, lmna-A antibody, fpl antibody, idc antibody, lfp antibody, cddc antibody, emd2 antibody, fpld antibody, hgps antibody, ldp1 antibody, lmn1 antibody, lmnc antibody, pro1 antibody, cdcd1 antibody, cmd1a antibody, cmt2b1 antibody, lgmd1b antibody, Lamin-A antibody, lamin-L(III)-like antibody, lamin A/C antibody, lamin A antibody, Lamin antibody, lamin A/C L homeolog antibody, lamin-L(III)-like antibody, LMNA antibody, Lmna antibody, Lam antibody, lmna antibody, lmna.L antibody, LMINA antibody

背景

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Alias Symbols: LMNA, LMN1,

Protein Interaction Partner: LMNA, RAPGEF2, FUS, KRTAP10-3, KRTAP10-7, DUSP13, UBC, TP53, SUMO2, SUMO3, MDM2, EED, KIAA0196, ROCK2, ZW10, NCL, EEF1D, PSMD10, GMPPB, KPNA6, KCTD12, PARK2, FBXO6, YWHAQ, ZNF280C, PGRMC2, SCML2, HNRNPR, TRIM28, ZBTB33, NUP153, THRAP3, USP15, POM121, DDX4

Protein Size: 664

基因ID

4000

UniProt

P02545

途径

Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus