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IBTK 抗体 (C-Term)

IBTK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514895
发货至: 中国
  • 抗原 See all IBTK 抗体
    IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    宿主
    • 26
    • 2
    克隆类型
    • 28
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IBTK antibody is un-conjugated
    应用范围
    • 20
    • 15
    • 13
    • 12
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    GDIFLKEEIN MEQNHSETMF KKAKTKAKKK PRKRSDSSGG YNLSDIIQSP
    产品特性
    This is a rabbit polyclonal antibody against IBTK. It was validated on Western Blot.
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human IBTK
    Top Product
    Discover our top product IBTK Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
    别名
    IBTK (IBTK 产品)
    别名
    IBTK antibody, fi40c08 antibody, wu:fi40c08 antibody, DKFZp468J085 antibody, BTBD26 antibody, BTKI antibody, RP1-93K22.1 antibody, 5430411K16Rik antibody, AA409502 antibody, mKIAA1417 antibody, inhibitor of Bruton tyrosine kinase antibody, inhibitor of Bruton agammaglobulinemia tyrosine kinase antibody, inhibitor of Bruton tyrosine kinase L homeolog antibody, IBTK antibody, ibtk antibody, Ibtk antibody, ibtk.L antibody
    背景
    Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    Alias Symbols: IBTK, BTKI, KIAA1417,

    Protein Interaction Partner: IGSF8, CD81, LAMTOR3, ITK, BTK, AKT1, PRKD1, PRKCG, PRKCE, PRKCD, PRKCB, PRKCA, PLCG1, CUL3, PPP1CA, UBC, RGS2,

    Protein Size: 1353
    基因ID
    25998
    NCBI登录号
    NP_056340
    UniProt
    Q9P2D0
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