Phospholipase C gamma 2 抗体 (Middle Region)
Quick Overview for Phospholipase C gamma 2 抗体 (Middle Region) (ABIN5514741)
抗原
See all Phospholipase C gamma 2 (PLCG2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ETHLRCAEFE LRLTDPVPNP NPHESKPWYY DSLSRGEAED MLMRIPRDGA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PLCG2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human PLCG2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Phospholipase C gamma 2 (PLCG2)
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别名
- PLCG2
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背景
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The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.
Alias Symbols: PLCG2,
Protein Interaction Partner: UBC, ZNF512B, ERBB2, EGFR, PRKCA, PLD1, IRS1, BLNK, LAT2, LIME1, GAB2, DAPP1, PRKD1, CBLB, GAB1, KHDRBS1, LAT, SH3BP2, LCP2, TEC, SHC1, PLCG2, SYK, BTK, KDR, BLK, ITK, LYN, FLT1, NPM1, LCK, JAK2, JAK1, FCER1G, HCK, FYN, EPOR, CD19, PLXNB1, VAV1, PTPN11,
Protein Size: 1265 -
基因ID
- 5336
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NCBI登录号
- NM_002661, NP_002652
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UniProt
- P16885
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途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
抗原
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