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PCGF2 抗体 (Middle Region)

PCGF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514708
发货至: 中国
  • 抗原 See all PCGF2 抗体
    PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
    抗原表位
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 42
    • 17
    • 15
    宿主
    • 39
    • 2
    • 1
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCGF2 antibody is un-conjugated
    应用范围
    • 37
    • 20
    • 13
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    EQEKGALSDD EIVSLSIEFY EGARDRDEKK GPLENGDGDK EKTGVRFLRC
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human PCGF2
    Top Product
    Discover our top product PCGF2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
    别名
    PCGF2 (PCGF2 产品)
    别名
    ZNF144 antibody, PCGF2 antibody, MEL-18 antibody, RNF110 antibody, Mel18 antibody, Rnf110 antibody, Zfp144 antibody, mel-18 antibody, polycomb group ring finger 2 antibody, PCGF2 antibody, Pcgf2 antibody
    背景
    The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

    Alias Symbols: MEL-18, RNF110, ZNF144,

    Protein Size: 344
    基因ID
    7703
    NCBI登录号
    NM_007144, NP_009075
    UniProt
    P35227
    途径
    Chromatin Binding
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