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CARD11 抗体 (Middle Region)

CARD11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514600
发货至: 中国
  • 抗原 See all CARD11 抗体
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 34
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 32
    • 1
    • 1
    • 1
    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD11 antibody is un-conjugated
    应用范围
    • 27
    • 11
    • 10
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    SPRLSRASFL FGQLLQFVSR SENKYKRMNS NERVRIISGS PLGSLARSSL
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CARD11
    Top Product
    Discover our top product CARD11 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    别名
    CARD11 (CARD11 产品)
    别名
    BENTA antibody, BIMP3 antibody, CARMA1 antibody, PPBL antibody, 0610008L17Rik antibody, 2410011D02Rik antibody, CARD11 antibody, LOC100232755 antibody, caspase recruitment domain family member 11 antibody, caspase recruitment domain family, member 11 antibody, caspase recruitment domain-containing protein 11 antibody, CARD11 antibody, Card11 antibody, LOC100550812 antibody, card11 antibody
    背景
    The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

    Alias Symbols: PPBL, BENTA, BIMP3, IMD11, CARMA1

    Protein Size: 1171
    基因ID
    84433
    NCBI登录号
    NM_032415, NP_115791
    UniProt
    Q8TES3
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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