C14orf169 + NO66 抗体 (Middle Region)
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- 抗原 See all C14orf169 + NO66 (C14orf169) 抗体
- C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C14orf169 + NO66 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EAILPLAVQA AMEENVEFRR GLPRDFMDYM GAQHSDSKDP RRTAFMEKVR
- 产品特性
- This is a rabbit polyclonal antibody against NO66. It was validated on Western Blot.
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human NO66
- Top Product
- Discover our top product C14orf169 Primary Antibody
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anti-Chromosome 14 Open Reading Frame 169 (C14orf169) (AA 1-641) antibody
C14orf169 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Chromosome 14 Open Reading Frame 169 (C14orf169) antibodyC14orf169 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 14 Open Reading Frame 169 (C14orf169) (AA 67-116) antibodyC14orf169 适用: 人, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 14 Open Reading Frame 169 (C14orf169) (Internal Region) antibodyVerified C14orf169 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Chromosome 14 Open Reading Frame 169 (C14orf169) (N-Term) antibodyC14orf169 适用: 人, Cow, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))
- 别名
- NO66 (C14orf169 产品)
- 别名
- LOC453015 antibody, C10H14orf169 antibody, MAPJD antibody, NO66 antibody, ROX antibody, C14orf169 antibody, No66 antibody, im:7141580 antibody, no66 antibody, chromosome 14 open reading frame 169 antibody, ribosomal oxygenase 1 antibody, chromosome 5 open reading frame, human C14orf169 antibody, LOC453015 antibody, Bm1_08415 antibody, RIOX1 antibody, C5H14ORF169 antibody, Riox1 antibody, riox1 antibody
- 背景
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NO66 is an oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically It demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). It also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). It may also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.
Alias Symbols: NO66, C14orf169, MAPJD,
Protein Interaction Partner: KAT5, TRRAP, MYC, USP42,
Protein Size: 429 - 基因ID
- 79697
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