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- 抗原 See all FOXO1 抗体
- FOXO1 (Forkhead Box O1 (FOXO1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FOXO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit polyclonal antibody raised against synthetic peptide of FOXO1.
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Antibody Reactive Against Synthetic Peptide.
- 免疫原
- A synthetic peptide corresponding to residues surrounding S256 of human FOXO1.
- Top Product
- Discover our top product FOXO1 Primary Antibody
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- 应用备注
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Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In PBS, 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
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Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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PKC? haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes." in: Molecular endocrinology (Baltimore, Md.), Vol. 28, Issue 7, pp. 1097-107, (2014) (PubMed).
: "Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation." in: Journal of lipid research, Vol. 56, Issue 1, pp. 70-80, (2014) (PubMed).
: "Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors." in: Journal of neurochemistry, Vol. 93, Issue 5, pp. 1209-19, (2005) (PubMed).
: "Protein kinase CK2 phosphorylates and upregulates Akt/PKB." in: Cell death and differentiation, Vol. 12, Issue 6, pp. 668-77, (2005) (PubMed).
: "Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity." in: The Journal of cell biology, Vol. 169, Issue 2, pp. 331-9, (2005) (PubMed).
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PKC? haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes." in: Molecular endocrinology (Baltimore, Md.), Vol. 28, Issue 7, pp. 1097-107, (2014) (PubMed).
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- 抗原
- FOXO1 (Forkhead Box O1 (FOXO1))
- 别名
- FOXO1A (FOXO1 产品)
- 别名
- FKH1 antibody, FKHR antibody, FOXO1A antibody, FoxO1a.1 antibody, foxo1 antibody, zgc:153388 antibody, Fkhr antibody, Foxo1a antibody, AI876417 antibody, Afxh antibody, Fkhr1 antibody, fkh1 antibody, fkhr antibody, foxo1a antibody, xFoxO1 antibody, FoxO1A antibody, foxo1a.2 antibody, forkhead box O1 antibody, forkhead box O1 a antibody, forkhead box O1 L homeolog antibody, forkhead box O1 b antibody, FOXO1 antibody, foxo1a antibody, Foxo1 antibody, foxo1 antibody, foxo1.L antibody, foxo1b antibody
- 基因ID
- 2308
- 途径
- PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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