PDPK1 抗体 (3-phosphoinositide Dependent Protein Kinase-1)

Details for Product anti-PDPK1 Antibody No. ABIN545485
抗原
适用

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宿主

393
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克隆类型
多克隆
标记
This PDPK1 antibody is un-conjugated
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14
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11
7
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应用范围
ELISA, Western Blotting (WB)
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选项
原理 Rabbit polyclonal antibody raised against synthetic peptide of PDK1.
免疫原 A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PDK1.
交叉反应 小鼠
抗原
别名 PDK1 (PDPK1 Antibody 摘要)
途径 PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
应用备注 ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
限制 仅限研究用
缓冲液 In PBS (0.09 % sodium azide)
储存条件 4 °C,-20 °C
储存方法 Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
厂商提供的图像
Image no. 1 for anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) antibody (ABIN545485) The PDK1 polyclonal antibody is used in Western blot to detect PDK1 in mouse kidney ...
有引用在: Sato, Fujita, Tsuruo: "Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3." in: The Journal of biological chemistry, Vol. 277, Issue 42, pp. 39360-7, 2002 (PubMed).

Frödin, Antal, Dümmler, Jensen, Deak, Gammeltoft, Biondi: "A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation." in: The EMBO journal, Vol. 21, Issue 20, pp. 5396-407, 2002 (PubMed).

King, Zenke, Dawson, Dutil, Newton, Hemmings, Bokoch: "Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1." in: The Journal of biological chemistry, Vol. 275, Issue 24, pp. 18108-13, 2000 (PubMed).