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- 抗原 See all SCNN1B 抗体
- SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))
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抗原表位
- AA 617-638
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SCNN1B antibody is conjugated to Atto 594
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Detects ~87 kDa.
- 交叉反应
- 小鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Synthetic peptide from the C-terminal of Rat ENaC beta (aa. 617-638)
- 克隆位点
- 7B8
- 亚型
- IgG1
- Top Product
- Discover our top product SCNN1B Primary Antibody
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anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (AA 554-640) antibody
SCNN1B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (C-Term) antibodySCNN1B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (pSer633) antibodySCNN1B 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (C-Term) antibodySCNN1B 适用: 人, 小鼠, 大鼠, Cow, 猴, 山羊, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (AA 406-640) antibodySCNN1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (AA 401-500) antibodySCNN1B 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (pThr615) antibodySCNN1B 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (AA 617-638) antibody (Biotin)SCNN1B 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 7B8 Biotin
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (AA 617-638) antibody (PE)SCNN1B 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 7B8 PE
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (AA 617-638) antibody (PerCP)SCNN1B 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 7B8 PerCP
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- 应用备注
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- WB (1:1000)
- IHC (1:150)
- optimal dilutions for assays should be determined by the user.
- 说明
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A 1:1000 dilution of ABIN5066879 was sufficient for detection of ENaC beta in 15 μg of Mouse whole kidney lysate by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))
- 别名
- ENaC beta (SCNN1B 产品)
- 别名
- BESC1 antibody, ENaCb antibody, ENaCbeta antibody, SCNEB antibody, RNENACB antibody, besc1 antibody, betaxENaC antibody, enacb antibody, enacbeta antibody, scnn1b antibody, beta-ENaC antibody, scneb antibody, SCNN1B antibody, BETA-ENAC antibody, sodium channel epithelial 1 beta subunit antibody, sodium channel, non voltage gated 1 beta subunit L homeolog antibody, sodium channel, non voltage gated 1 beta subunit antibody, sodium channel, nonvoltage-gated 1 beta antibody, sodium channel, non voltage gated 1 beta subunit S homeolog antibody, SCNN1B antibody, Scnn1b antibody, scnn1b.L antibody, scnn1b antibody, scnn1b.S antibody
- 背景
- The Epithelial Sodium Channel (ENaC) is a membrane ion channel permeable to Na+ ions. It is located in the apical plasma membrane of epithelia in the kidneys, lung, colon, and other tissues where it plays a role in trans epithelial Na+-ion transport (1). Specifically Na+ transport via ENaC occurs across many epithelial surfaces, and plays a key role in regulating salt and water absorption (2). ENaCs are composed of three structurally related subunits that form a tetrameric channel, alpha, beta, and gamma. The expression of its alpha and beta subunits is enhanced as keratinocytes differentiate (3, 4). The beta and gamma-ENaC subunits are essential for edema fluid to exert its maximal effect on net fluid absorption by distal lung epithelia(5). And it has been concluded that the subunits are differentially expressed in the retina of mice with ocular hypertension, therefore the up-regulation of alpha-ENaC proteins could serve as a protection mechanism against elevated intraocular pressure (6).
- 基因ID
- 24767
- NCBI登录号
- NP_036780
- UniProt
- P37090
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